Science.News
Feb 6, 2026
Key protein identified that could reverse brain aging
Researchers have identified an important protein that helps aging brains maintain the ability to regenerate neural stem cells — a process that is closely linked to learning and memory. The results show how age-related molecular changes impair this regenerative capacity and point to new biological pathways that could be used to slow down cognitive decline.
Source
“DMTF1 up-regulation rescues proliferation defect of telomere dysfunctional neural stem cells via the SWI/SNF-E2F axis” by Yajing Liang, Oleg V. Grinchuk, Nadia Omega Cipta, Yingying Zeng, You Heng Chuah, Jeehyun Yoon, Zi Jian Khong, Hui Ying Chow, Winanto Ng, Chin Tong Ong, Shuo-Chien Ling, Shi-Yan Ng, Yuin-Han Loh and Derrick Sek Tong Ong, January 2, 2026, Science Advances. DOI: 10.1126/sciadv.ady5905
