Science

Age-related brain diseases such as stroke, dementia, and depression can significantly impair the quality of life of older people. However, many of these diseases are preventable. A comprehensive, systematic study by researchers at Mass General Brigham has identified 17 modifiable risk factors that apply to all three disorders.

New research from the University of Ottawa shows that repeated immersion in cold water helps the body better manage cellular stress. After just one week of daily exposure to cold water, participants showed improved autophagy — a cellular “recycling” system — and fewer signs of damage. This adjustment could provide protection against illness and aging, suggesting that cold acclimatization could be more than just a wellness trend.

Using modern X-ray phase contrast tomography (XPCT), scientists have discovered how gut health can influence Alzheimer's disease. The study showed structural changes in the intestines of mice suffering from Alzheimer's disease, as well as abnormalities in intestinal cells, neurons, and mucus secretion.

Poor sleep quality impairs immune function and increases the risk of inflammation and disease. A lack of sleep at night can mimic the immune system changes seen in obesity, highlighting the importance of sleep for overall health.

44 people with mild cognitive impairment took part in the study. After six months, participants who had completed weight training showed improvements in memory and brain structure, while participants who had not done weight training had a worsening of the assessed parameters.