Science
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4.5.2025

The Underestimated Power of Metabolism

What are the secrets of long-lasting animal health and how can we apply these lessons to our own lives?

Giant Turtle in Water

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An international team of researchers has recently discovered a fascinating biological pattern: Many long-lived animals — from certain reptiles to primates — have a remarkably stable metabolic rate. Contrary to the current assumption that a slower metabolism alone leads to a longer life, it seems the stability to be decisive over time.

The core of the discovery

Not how fast but how constant the metabolism works is a potential key to healthy longevity. Even animals with relatively high energy consumption — such as apes — age comparatively slowly if their metabolic activity remains in balance.

What that means for us

The study opens up new perspectives on prevention and healthy lifestyles:

  • Regularity beats extremes. Fluctuations — such as those caused by crash diets, irregular sleep, or chronic stress — could be more harmful in the long term than a moderately higher basal metabolic rate.
  • Metabolic balance becomes a new destination. This means: a diet, exercise and lifestyle that does not overwhelm the body but brings it into a sustainable rhythm.
  • Rethinking Longevity Medicine. Instead of just “more antioxidants” or “fewer calories,” we need a deeper understanding of our inner rhythms — and how we maintain them.

Conclusion:
Longevity is less a question of “slowing down”, but of balance and resilience. A stable metabolism could play a central role in this — and may be consciously strengthened.

References

“The mammalian longevity associated acetylome” by S. Feldman-Trabelsi, N. Touitou, R. Nagar, Z. Schwartz, A. Michelson, S. Shaki, M. Y. Avivi, B. Lerrer, S. Snir and H. Y. Cohen, April 22, 2025, Nature Communications.

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Glossary

An international team of researchers has recently discovered a fascinating biological pattern: Many long-lived animals — from certain reptiles to primates — have a remarkably stable metabolic rate. Contrary to the current assumption that a slower metabolism alone leads to a longer life, it seems the stability to be decisive over time.

The core of the discovery

Not how fast but how constant the metabolism works is a potential key to healthy longevity. Even animals with relatively high energy consumption — such as apes — age comparatively slowly if their metabolic activity remains in balance.

What that means for us

The study opens up new perspectives on prevention and healthy lifestyles:

  • Regularity beats extremes. Fluctuations — such as those caused by crash diets, irregular sleep, or chronic stress — could be more harmful in the long term than a moderately higher basal metabolic rate.
  • Metabolic balance becomes a new destination. This means: a diet, exercise and lifestyle that does not overwhelm the body but brings it into a sustainable rhythm.
  • Rethinking Longevity Medicine. Instead of just “more antioxidants” or “fewer calories,” we need a deeper understanding of our inner rhythms — and how we maintain them.

Conclusion:
Longevity is less a question of “slowing down”, but of balance and resilience. A stable metabolism could play a central role in this — and may be consciously strengthened.

Experte

Munster

Dr. Ulrich Frohberger

Referenzen

“The mammalian longevity associated acetylome” by S. Feldman-Trabelsi, N. Touitou, R. Nagar, Z. Schwartz, A. Michelson, S. Shaki, M. Y. Avivi, B. Lerrer, S. Snir and H. Y. Cohen, April 22, 2025, Nature Communications.

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