NMN: The Secret to Slowing Down the Process of Aging
Why NMN is one of the most promising supplements for a longer and healthier life
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In search of the secret to a longer and healthier life, science has focused intensively on dietary supplements that can slow down the aging process. In this context, a specific molecule, nicotinamide mononucleotide (NMN), plays an outstanding role. NMN, a precursor of NAD+ (nicotinamide adenine dinucleotide), has the potential to counteract the natural breakdown of NAD+ in the body and thus optimize health.
What is NMN?
NMN, or nicotinamide mononucleotide, is a naturally occurring vitamin B3 derivative and an essential component of NAD+. This coenzyme is found in all living cells and plays an important role in fighting signs of aging and diseases. However, as we age, NAD+ levels decrease. This is where NMN comes in by counteracting this decline and replenishing NAD+ levels in the body.
Natural sources of NMN
NMN is found in a wide variety of foods including milk, meat, avocado, broccoli, cabbage, cucumbers, and edamame. Despite its presence in food, however, it would be almost impossible to obtain a sufficient amount through diet alone. To get just 250 mg of NMN, you would have to eat almost 100 kg of broccoli or 416 kg of beef, for example.
Key features of NMN
NMN serves as a precursor to NAD+ and is involved in a variety of metabolic processes in the body. NAD+ helps convert nutrients into energy and serves as fuel for enzymes that protect and repair DNA. As we age, NAD+ levels in the body decrease, which can lead to an accelerated aging process and reduced life expectancy. Increasing NAD+ levels through NMN supplementation provides many health benefits for various organs, including the brain, cardiovascular system, and skin elasticity.
Benefits of taking NMN
NMN supplementation aims to counteract the body's natural decline of NAD+ as we age. By restoring NAD+ levels, NMN supplementation can help maintain health and energy over time. Studies have shown that NMN can have positive effects on energy levels, memory, blood vessel health, metabolism, stem cell health, epigenome preservation, and repair DNA damage. For example, a clinical trial led by Dr. David Sinclair, an expert in biological aging, has shown that NMN can extend lifespan, while other studies have shown that NMN increases NAD+ levels and repair DNA damage.
NMN has the potential to change the way we look at aging by improving health and slowing down the aging process as a precursor to NAD+. With promising clinical results and a solid scientific base, NMN is considered a key player in the search for a longer and healthier life. Its ability to increase NAD+ levels in the body makes it a promising dietary supplement for slowing down the aging process. Ongoing clinical trials demonstrate the safety, stability, and effectiveness of NMN and point to other potential benefits.
This potential also has Avea, a leading manufacturer of NMN-Dietary supplements, recognized. Through its high-quality formula and collaboration with renowned experts in the field of longevity research, Avea strives to develop innovative products that improve health and quality of life. With a clear focus on quality and effectiveness, Avea is determined to help people regain and maintain their health and energy at youthful levels.
Avea capsules contain 250 mg NMN β-nicotinamide mononucleotide and have been tested twice in Switzerland to ensure 99% purity.
Avea recommends taking one capsule daily, although there may be an increase in energy and an improvement in skin elasticity and hydration in the first few weeks of use, followed by a reduction in inflammation and an improvement in cognitive function after a few months. In the long term, you can expect to feel and look younger and even reverse your biological age. To achieve a synergy effect, Avea recommends taking it with its booster product.
Use this link to get a discounted offer.
References
- Rajman, L., Chwalek, K, & Sinclair, DA (2018). Therapeutic potential of NAD-enhancing molecules: The in vivo evidence. Cell Metabolism, 27 (3), 529—547. https://doi.org/10.1016/j.cmet.2018.02 .011
- North, BJ, Rosenberg, MA, Jeganathan, KB, Hafner, AV, Michan, S., Dai, J., Baker, DJ, Cen, Y., Wu, LE, Sauve, AA, van Deursen, JM, Rosenzweig, A., & Sinclair, DA (2014). SIRT2 induces checkpoint kinase BuBr1 to extend lifespan. The EMBO Journal, 33 (13), 1438—1453. https://doi.org/10.15252/embj.201386907
- Li, J., Bonkowski, MS, Moniot, S., Zhang, D., Hubbard, BP, Ling, AJ, Rajman, LA, Qin, B., Lou, Z., Gorbunova, V., Aravind, L., Steegborn, C., & Sinclair, DA (2017). A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science (New York, NY), 355 (6331), 1312—1317. https://doi.org/10.1126/science.aad8242
- Kiss, T., Nyúl-Toth, A., Balasubramanian, P., Tarantini, S., Ahire, C., Yabluchanskiy, A., Csipo, T., Farkas, E., Wren, J.D., Garman, L., Csiszar, A., & Ungvari, Z. (2020). Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory and anti-apoptotic effects. GeroScience, 42 (2), 527-546. https://doi.org/10.1007/s11357-020-00165 -5
- Yoshino, M., Yoshino, J., Kayser, B.D., Patti, G.J., Franczyk, M.P., Mills, K.F., Sindelar, M., Pietka, T., Patterson, B.W., Imai, S.I., & Klein, S. (2021). Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science (New York, NY), 372 (6547), 1224—1229. https://doi.org/10.1126/science.abe9985
Publiziert
7.5.2024
Kategorie
Lifestyle
In search of the secret to a longer and healthier life, science has focused intensively on dietary supplements that can slow down the aging process. In this context, a specific molecule, nicotinamide mononucleotide (NMN), plays an outstanding role. NMN, a precursor of NAD+ (nicotinamide adenine dinucleotide), has the potential to counteract the natural breakdown of NAD+ in the body and thus optimize health.
What is NMN?
NMN, or nicotinamide mononucleotide, is a naturally occurring vitamin B3 derivative and an essential component of NAD+. This coenzyme is found in all living cells and plays an important role in fighting signs of aging and diseases. However, as we age, NAD+ levels decrease. This is where NMN comes in by counteracting this decline and replenishing NAD+ levels in the body.
Natural sources of NMN
NMN is found in a wide variety of foods including milk, meat, avocado, broccoli, cabbage, cucumbers, and edamame. Despite its presence in food, however, it would be almost impossible to obtain a sufficient amount through diet alone. To get just 250 mg of NMN, you would have to eat almost 100 kg of broccoli or 416 kg of beef, for example.
Key features of NMN
NMN serves as a precursor to NAD+ and is involved in a variety of metabolic processes in the body. NAD+ helps convert nutrients into energy and serves as fuel for enzymes that protect and repair DNA. As we age, NAD+ levels in the body decrease, which can lead to an accelerated aging process and reduced life expectancy. Increasing NAD+ levels through NMN supplementation provides many health benefits for various organs, including the brain, cardiovascular system, and skin elasticity.
Benefits of taking NMN
NMN supplementation aims to counteract the body's natural decline of NAD+ as we age. By restoring NAD+ levels, NMN supplementation can help maintain health and energy over time. Studies have shown that NMN can have positive effects on energy levels, memory, blood vessel health, metabolism, stem cell health, epigenome preservation, and repair DNA damage. For example, a clinical trial led by Dr. David Sinclair, an expert in biological aging, has shown that NMN can extend lifespan, while other studies have shown that NMN increases NAD+ levels and repair DNA damage.
NMN has the potential to change the way we look at aging by improving health and slowing down the aging process as a precursor to NAD+. With promising clinical results and a solid scientific base, NMN is considered a key player in the search for a longer and healthier life. Its ability to increase NAD+ levels in the body makes it a promising dietary supplement for slowing down the aging process. Ongoing clinical trials demonstrate the safety, stability, and effectiveness of NMN and point to other potential benefits.
This potential also has Avea, a leading manufacturer of NMN-Dietary supplements, recognized. Through its high-quality formula and collaboration with renowned experts in the field of longevity research, Avea strives to develop innovative products that improve health and quality of life. With a clear focus on quality and effectiveness, Avea is determined to help people regain and maintain their health and energy at youthful levels.
Avea capsules contain 250 mg NMN β-nicotinamide mononucleotide and have been tested twice in Switzerland to ensure 99% purity.
Avea recommends taking one capsule daily, although there may be an increase in energy and an improvement in skin elasticity and hydration in the first few weeks of use, followed by a reduction in inflammation and an improvement in cognitive function after a few months. In the long term, you can expect to feel and look younger and even reverse your biological age. To achieve a synergy effect, Avea recommends taking it with its booster product.
Use this link to get a discounted offer.
Referenzen
- Rajman, L., Chwalek, K, & Sinclair, DA (2018). Therapeutic potential of NAD-enhancing molecules: The in vivo evidence. Cell Metabolism, 27 (3), 529—547. https://doi.org/10.1016/j.cmet.2018.02 .011
- North, BJ, Rosenberg, MA, Jeganathan, KB, Hafner, AV, Michan, S., Dai, J., Baker, DJ, Cen, Y., Wu, LE, Sauve, AA, van Deursen, JM, Rosenzweig, A., & Sinclair, DA (2014). SIRT2 induces checkpoint kinase BuBr1 to extend lifespan. The EMBO Journal, 33 (13), 1438—1453. https://doi.org/10.15252/embj.201386907
- Li, J., Bonkowski, MS, Moniot, S., Zhang, D., Hubbard, BP, Ling, AJ, Rajman, LA, Qin, B., Lou, Z., Gorbunova, V., Aravind, L., Steegborn, C., & Sinclair, DA (2017). A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science (New York, NY), 355 (6331), 1312—1317. https://doi.org/10.1126/science.aad8242
- Kiss, T., Nyúl-Toth, A., Balasubramanian, P., Tarantini, S., Ahire, C., Yabluchanskiy, A., Csipo, T., Farkas, E., Wren, J.D., Garman, L., Csiszar, A., & Ungvari, Z. (2020). Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory and anti-apoptotic effects. GeroScience, 42 (2), 527-546. https://doi.org/10.1007/s11357-020-00165 -5
- Yoshino, M., Yoshino, J., Kayser, B.D., Patti, G.J., Franczyk, M.P., Mills, K.F., Sindelar, M., Pietka, T., Patterson, B.W., Imai, S.I., & Klein, S. (2021). Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science (New York, NY), 372 (6547), 1224—1229. https://doi.org/10.1126/science.abe9985
Publiziert
7.5.2024
Kategorie
Lifestyle
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