Science.News
19.4.2024

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Science.News
Apr 19, 2024

Less epigenetic noise in people who live longer

In a groundbreaking study published in the journal Aging Cell, researchers have found that longer-living Chinese women have less epigenetic noise in critical areas of their genomes. This finding is based on previous research that has linked an accumulation of epigenetic noise to age-related diseases such as Alzheimer's and vascular disorders. The team analyzed samples from different age groups and found that although the total entropy of methylation increases with age, the entropy in long-lived people is more like that of people 40 years younger. Interestingly, these long-lived individuals had significantly lower entropy for genes that are considered essential, suggesting a potential protective mechanism against age-related diseases.

Source

https://doi.org/10.1111/acel.14163

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