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Experts explain why a healthy gut is important

A simple analysis of the microbiome can provide information about the state of our health

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The microbiome is the entirety of all microbes, such as bacteria, fungi, viruses and their genes, that live naturally on and in our bodies. Although microbes are so small that you can only see them with a microscope, they contribute significantly to human health and wellbeing. They protect us from pathogens, help develop our immune system and enable us to digest food for energy.

Because the microbiome is an important interface between the body and the environment, these microbes can influence health in a variety of ways and even influence how we react to specific environmental substances.

How can the microbiome influence health?

The crucial role of the microbiome is not surprising when you consider that it is in the body There are more microbes than human cells. The human microbiome is diverse, and every part of the body — for example the intestines, skin, and oral and nasal cavities — has a different microbial community.

A person's core microbiome is formed in the first few years of life, but can change over time in response to various factors, such as diet, medication, and environmental influences. This can result in digestive problems, a weakened immune system, mood swings and even depression, weight gain, and skin problems. The best way to identify an imbalance in the intestines is to do a microbiome test. However, thanks to rapid developments in research, you no longer have to go to a doctor, but can do it comfortably at home.

For example, with the MyBioma test from the young Austrian company of the same name. We have the founders Dr. Barbara Sladek and Dr. Nikolaus Gasche asked to tell us something about their microbiome analysis.

myBioma founders Dr. Barbara Sladek and Dr. Nikolaus Gasche

Why is it important to know your microbiome?

Each person has their own individual microbiome, which consists of bacteria, viruses, fungi, and other organisms, most of which live in their intestines. The gut microbiome has a significant impact on health and wellbeing of a person. The bacteria in your intestines influence digestive problems such as diarrhea, constipation, and flatulence, as well as the metabolism of sugar, protein, and fat. The weight and health of organs such as the liver and cardiovascular system are also closely linked to bacteria in the gut microbiome.

What exactly is the myBioma test and why was it developed?

The myBIOMA analysis is a scientifically based intestinal microbiome (= colloquially known as intestinal flora) analysis for use at home. Based on the analysis, everyone can gain knowledge about their intestinal bacteria. The analysis can be performed discreetly at home without a doctor or therapist.

Through the analysis, you can find out what the balance of intestinal bacteria is doing, because the Intestinal bacteria have a significant impact on our overall health and wellbeing. The bacteria that live there decide whether we are prone to digestive problems such as diarrhea, constipation or flatulence, how we utilize sugar, protein and fat, and how this affects our metabolism. But our weight and the health of our liver or cardiovascular system are also closely linked to the bacteria living in our intestinal microbiome.

The myBioma analysis was developed to give all people the opportunity to know and better understand their intestinal microbiome.

How is the result determined and what is necessary for this?

To carry out the analysis, State-of-the-art next-generation DNA sequencing technologies(NGS) and bioinformatic methods used to identify the various types of microorganisms in the intestine and to determine the connection to various health conditions. More specifically, MyBioma analysis is a method in which bacterial DNA is isolated from a stool sample. A specific gene (16S), which is found in all bacteria, is amplified using polymerase chain reaction (PCR) and then analyzed using next-generation DNA sequencing (NGS). NGS is a precise method for determining the individual base pairs in DNA. By analyzing sequence data using a special phylogenetic analysis algorithm, culturable and non-cultivable bacteria are identified, which leads to the determination of the individual bacterial intestinal microbiome.

What distinguishes the myBioma test from competing products?

On average, conventional analyses only examine around 10 different types of bacteria. For this analysis, the culture method is often used, in which the stool is spread onto a nutrient medium (Petri dish) to observe bacterial growth. The result only provides information about whether a few important strains of the microbiome are present, which is very imprecise and scientifically irrelevant. The advantage of this method is that it is inexpensive and the result is available within a few days.

In contrast, MyBioma can use 16S gene sequencing identify over 1,400 different types of bacteria. Microbial DNA analysis is carried out using the latest biotechnological next-generation sequencing method. Due to the complexity of the analysis, it takes around 3-4 weeks for the sample to be fully analyzed. In addition, you get scientifically based information about associations with diseases, which can cause the bacteria, as well as suitable dietary recommendations for sustainable optimization microbiome health. All statements in the report are backed up with scientific publications.

What can the user expect from the test?

Users get a comprehensive overview about all bacteria in your intestines, including Species richness, diversity, species equality and probiotic bacteria. They also learn what effects their intestinal bacteria have on their food intake, including enterotype, calorie intake, sugar, fat, vitamin and protein metabolism. The analysis also provides information about which health conditions their bacteria are associated with, such as inflammation, intestinal mucosa, irritable bowel syndrome, weight management, gut-brain axis, gut-liver axis, gut-skin axis, insulin balance and joint health. Based on the results, they receive practical suggestions for improvement that can be easily integrated into everyday life in order to optimize the health of their microbiome.

Are the analysis, recommendations and suggestions easy to understand and implement, or does myBioma provide assistance in the form of advice?

The myBioma diet suggestions are Comprehensibly formulated and easy to implementso that myBioma customers can benefit from it. Should any questions arise, the MyBioma employees are available and are also happy to offer a Report meeting on. In addition, myBioma is Therapist tool ready where customers can book appointments with healthcare professionals.

References

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Glossary

The microbiome is the entirety of all microbes, such as bacteria, fungi, viruses and their genes, that live naturally on and in our bodies. Although microbes are so small that you can only see them with a microscope, they contribute significantly to human health and wellbeing. They protect us from pathogens, help develop our immune system and enable us to digest food for energy.

Because the microbiome is an important interface between the body and the environment, these microbes can influence health in a variety of ways and even influence how we react to specific environmental substances.

How can the microbiome influence health?

The crucial role of the microbiome is not surprising when you consider that it is in the body There are more microbes than human cells. The human microbiome is diverse, and every part of the body — for example the intestines, skin, and oral and nasal cavities — has a different microbial community.

A person's core microbiome is formed in the first few years of life, but can change over time in response to various factors, such as diet, medication, and environmental influences. This can result in digestive problems, a weakened immune system, mood swings and even depression, weight gain, and skin problems. The best way to identify an imbalance in the intestines is to do a microbiome test. However, thanks to rapid developments in research, you no longer have to go to a doctor, but can do it comfortably at home.

For example, with the MyBioma test from the young Austrian company of the same name. We have the founders Dr. Barbara Sladek and Dr. Nikolaus Gasche asked to tell us something about their microbiome analysis.

myBioma founders Dr. Barbara Sladek and Dr. Nikolaus Gasche

Why is it important to know your microbiome?

Each person has their own individual microbiome, which consists of bacteria, viruses, fungi, and other organisms, most of which live in their intestines. The gut microbiome has a significant impact on health and wellbeing of a person. The bacteria in your intestines influence digestive problems such as diarrhea, constipation, and flatulence, as well as the metabolism of sugar, protein, and fat. The weight and health of organs such as the liver and cardiovascular system are also closely linked to bacteria in the gut microbiome.

What exactly is the myBioma test and why was it developed?

The myBIOMA analysis is a scientifically based intestinal microbiome (= colloquially known as intestinal flora) analysis for use at home. Based on the analysis, everyone can gain knowledge about their intestinal bacteria. The analysis can be performed discreetly at home without a doctor or therapist.

Through the analysis, you can find out what the balance of intestinal bacteria is doing, because the Intestinal bacteria have a significant impact on our overall health and wellbeing. The bacteria that live there decide whether we are prone to digestive problems such as diarrhea, constipation or flatulence, how we utilize sugar, protein and fat, and how this affects our metabolism. But our weight and the health of our liver or cardiovascular system are also closely linked to the bacteria living in our intestinal microbiome.

The myBioma analysis was developed to give all people the opportunity to know and better understand their intestinal microbiome.

How is the result determined and what is necessary for this?

To carry out the analysis, State-of-the-art next-generation DNA sequencing technologies(NGS) and bioinformatic methods used to identify the various types of microorganisms in the intestine and to determine the connection to various health conditions. More specifically, MyBioma analysis is a method in which bacterial DNA is isolated from a stool sample. A specific gene (16S), which is found in all bacteria, is amplified using polymerase chain reaction (PCR) and then analyzed using next-generation DNA sequencing (NGS). NGS is a precise method for determining the individual base pairs in DNA. By analyzing sequence data using a special phylogenetic analysis algorithm, culturable and non-cultivable bacteria are identified, which leads to the determination of the individual bacterial intestinal microbiome.

What distinguishes the myBioma test from competing products?

On average, conventional analyses only examine around 10 different types of bacteria. For this analysis, the culture method is often used, in which the stool is spread onto a nutrient medium (Petri dish) to observe bacterial growth. The result only provides information about whether a few important strains of the microbiome are present, which is very imprecise and scientifically irrelevant. The advantage of this method is that it is inexpensive and the result is available within a few days.

In contrast, MyBioma can use 16S gene sequencing identify over 1,400 different types of bacteria. Microbial DNA analysis is carried out using the latest biotechnological next-generation sequencing method. Due to the complexity of the analysis, it takes around 3-4 weeks for the sample to be fully analyzed. In addition, you get scientifically based information about associations with diseases, which can cause the bacteria, as well as suitable dietary recommendations for sustainable optimization microbiome health. All statements in the report are backed up with scientific publications.

What can the user expect from the test?

Users get a comprehensive overview about all bacteria in your intestines, including Species richness, diversity, species equality and probiotic bacteria. They also learn what effects their intestinal bacteria have on their food intake, including enterotype, calorie intake, sugar, fat, vitamin and protein metabolism. The analysis also provides information about which health conditions their bacteria are associated with, such as inflammation, intestinal mucosa, irritable bowel syndrome, weight management, gut-brain axis, gut-liver axis, gut-skin axis, insulin balance and joint health. Based on the results, they receive practical suggestions for improvement that can be easily integrated into everyday life in order to optimize the health of their microbiome.

Are the analysis, recommendations and suggestions easy to understand and implement, or does myBioma provide assistance in the form of advice?

The myBioma diet suggestions are Comprehensibly formulated and easy to implementso that myBioma customers can benefit from it. Should any questions arise, the MyBioma employees are available and are also happy to offer a Report meeting on. In addition, myBioma is Therapist tool ready where customers can book appointments with healthcare professionals.

Referenzen

Wissenschaftliche Begriffe

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Zum Glossar